Pycnogenol Slows Glucose Uptake
After Eating
Linda von Wartburg
15 April 2024
Upcoming research in the Journal of
Diabetes Research and Clinical Practice reveals that Pycnogenol (pik-naw-jin-all)
that many-talented extract of pine tree, is 190 times more effective than
the prescription medicine acarbose (Precose) in slowing uptake of glucose
after a meal, thereby preventing after-meal glucose spikes.
Slows Glucose Uptake After Eating
The study, conducted at University of
Wurzburg, Germany, by Dr. Petra Hogger, found that Pycnogenol worked by
inhibiting the intestinal enzyme alpha-glucosidase, which breaks down
complex carbohydrates such as starch and table sugar into glucose
molecules.
The high levels of procyanidins (flavonoids)
in Pycnogenol are particularly good at inhibiting alpha–glucosidase. As a
result, meal carbohydrates break down into glucose slowly and enter the
bloodstream more steadily, over a longer period of time. This prolongs a
feeling of fullness and reduces after-meal glucose spikes.
In two prior
2004 studies, Pycnogenol was found to lower blood sugar levels in type 2
patients. In March 2004, Diabetes Care showed that supplement
with Pycnogenol lowered after-meal and fasting blood glucose. The October
issue of Life
Sciences demonstrated further lowering of blood glucose in patients
already taking acarbose and metformin.
The Special Sauce
Pycnogenol is extracted from the bark of
maritime pine trees that grow on the coast of southwest France and contain
a unique combination of procyanidins, bioflavonoids, and organic acids.
Bioflavonoids, which are also found in fruits, help vitamin C function as
an antioxidant. Pycnogenol contains a group of bioflavonoids called
proanthocyanidins.
And It Helps Retinopathy Too!
Proanthocyanidins have been shown to
increase the elasticity of capillaries, the small blood vessels found in
the retina, thereby improving circulation.
In France, Pycnogenol is the number one
prescription for retinopathy, the diabetes-caused damage to blood vessels
in the retina that can lead to blindness.
According to a study in Phytotherapy
Research (15; 1-5; 2001), thirty people with diabetic retinopathy were
treated with 50-mg dosages of Pycnogenol three times per day for two
months. Another ten people were treated with a placebo. The researchers
found that Pycnogenol had a beneficial effect on retinopathy, while the
placebo group’s retinopathy worsened. Another study, published in the
journal Ophthalmic Research in 1996, demonstrated Pycnogenol’s
beneficial effects in cow and pig retinas.
More than 220 studies and reviews have been
published about Pycnogenol’s salutary effects, and it is available in more
than 600 supplements. The recommended daily dosage of Pycnogenol is one to
two 30-mg tablets.
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